Fig. 7.

Fluorescent confocal microscopy criteria for various subtypes of BCCs. (a, c, e) Submosaics show characteristic morphological features of BCCs: presence of fluorescence, nuclear pleomorphism, increased N/C ratio, and palisading in (a) superficial BCC, (c) nodular BCC, and (e) infiltrative BCC. The tumor islands (red arrows) are well demarcated in (c) nodular BCC and (e) infiltrative BCC than the (a) superficial BCC, whereas clefting (red arrowheads) appears more prominent in superficial BCC (a) and nodular BCC (c). (e) “Starry sky” (yellow asterisk) appearance of the tumor stroma is pronounced in infiltrative BCC. (b, d, f) And corresponding H&E-stained frozen histopathology ($10\times$). Scale bars: $\mathrm{A}=200\mu \mathrm{m}$; C & $\mathrm{E}=600\mu \mathrm{m}$.