Table 4. Arterial stiffness parameters.
Placebo | Curcumin | |||
---|---|---|---|---|
Week 0 | Week 12 | Week 0 | Week 12 | |
Carotid systolic blood pressure, mmHg | 117±5 | 116±5 | 123±4 | 123±4 |
Carotid pulse pressure, mmHg | 49±3 | 48±3 | 56±4 | 56±3 |
Carotid artery diameter at end-diastole, mmL | 6.35±0.2 | 6.35±0.2 | 6.41±0.1 | 6.38±0.2 |
Carotid change in diameter, mm | 0.35±0.02* | 0.36±0.02 | 0.45±0.03 | 0.44±0.03 |
Carotid augmentation index, % | 16±3 | 16±3 | 17±2 | 17±2 |
Carotid β-stiffness index, U | 10.3±0.7 | 9.4±0.5 | 9.1±0.6 | 9.2±0.5 |
Carotid to radial PWV, cm/s | 991±26 | 989±34 | 945±34 | 930±47 |
Radial augmentation index, % | −13±3 | −12±3 | −8±3 | −6±3 |
Carotid IMT at end diastole, mmL | 0.56±0.01 | 0.56±0.01 | 0.60±0.02 | 0.60±0.02 |
Data are mean±SE; PWV, pulse wave velocity; IMT, intima-media thickness;
Data log transformed for statistical analysis;
P=0.02 vs. curcumin week 0