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. 2017 Jan 10;9(1):209–246. doi: 10.18632/aging.101151

Figure 2. LocusZoom plots for the suggested top 10 SNPs (5 genes) associated with gait speed of the combined analysis.

Figure 2

Figure 2

Figure 2

Figure 2

Figure 2

(A) POM121L2; (B) HLA-DPB1, (C) UQCC2 (MNF1), (D) SASH1, (E) NCALD. In each plot, the −log10 of p values are on the left y-axis; the SNP genomic position (HG19) on the x-axis; the estimated recombination rate from 1000 genomes Nov. 2014 EUR are on the right y-axis and plotted in blue. The most significant SNP is in purple diamond and plotted using the p value attained from the meta-analysis. SNPs are colored to reflect linkage disequilibrium (LD) with the most significant SNP in red (pairwise r2 from 1000 genomes Nov. 2014 EUR). Gene annotations are from the SeattleSeqAnnotation141.