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. 2017 Jan 10;9(1):209–246. doi: 10.18632/aging.101151

Table 2. Top 10 association meta-analysis results for gait speed.

Screening Set (n=31,478) Validation Set (n=2,588) Screening + Validation Set (n=34,066)
SNP Chr.:Position E/NE Allele F E Allele Closest Gene Δ(kb)/gene location Beta (SE) P HetPVal Beta (SE) P Beta (SE) P
rs17527406 6:33709545 C/G 0.016 UQCC2(MNF1) intron 0.040(0.007) 5.22E-7 0.2669 0.014(0.032) 0.65 0.037(0.007) 6.883e-7
rs9501255* 6:33087321 T/C 0.038 HLA-DPB1 3′ UTR 0.023(0.005) 1.53e-6 0.5853 0.048(0.023) 0.04 0.024(0.005) 3.326e-7
rs7763822* 6:33092651 T/C 0.038 HLA-DPB1 3 0.023(0.005) 1.54e-6 0.5704 0.047(0.023) 0.04 0.024(0.005) 3.440e-7
rs3749985* 6:33086656 C/G 0.038 HLA-DPB1 3′ UTR 0.023(0.005) 1.55e-6 0.5856 0.048(0.023) 0.04 0.024(0.005) 3.385e-7
rs7746199# 6:27293545 C/T 0.166 POM121L2 15 0.011(0.002) 1.58E-6 0.9658 0.011(0.008) 0.19 0.011(0.002) 7.125e-7
rs12155739 8:102084750 C/T 0.030 NCALD intron −0.041(0.008) 2.04E-6 0.2076 −0.024(0.032) 0.45 −0.039(0.008) 1.858e-6
rs3800318# 6:27295862 A/T 0.830 POM121L2 13 −0.011(0.002) 2.07E-6 0.966 −0.011(0.008) 0.20 −0.011(0.002) 9.686e-7
rs13211166 6:27298161 A/T 0.190 POM121L2 11 0.011(0.002) 2.12E-6 0.9688 0.010(0.009) 0.24 0.010(0.002) 1.136e-6
rs9403969 6:148622038 T/G 0.737 SASH1 70 0.009(0.002) 2.34e-6 0.4004 0.005(0.007) 0.50 0.009(0.002) 2.351e-6
rs16897515# 6:27310241 A/C 0.161 POM121L2 missense 0.011(0.002) 2.41E-6 0.9505 0.007(0.009) 0.42 0.010(0.002) 2.080e-6

*First gene segment, #second gene segment. E/NE-Effect-, Non-Effect allele; F E-Frequency of Effect Allele; Δ-distance to proximal gene; HetPVal- Heterogeneity P Value.