Fig. 4.

Effects of diet on cardiac function. (a) High resolution cardiac magnetic resonance tissue tagging image in the short-axis, midventricular orientation. (b) Illustrative deformation pattern of a short-axis tissue tagging image progressing from diastole to systole. Note the grid-shortening pattern in the circumferential direction representing circumferential strain. (c) Schematic representation of left ventricular torsion, illustrating basal to apical rotation. (d) Circumferential strain throughout the cardiac cycle in a representative dog at baseline (black line) and after 6 weeks of control diet feeding (grey line). (e) Left ventricular twisting pattern (torsion) throughout one cardiac cycle in a representative dog at baseline (black line) and after 6 weeks of control diet feeding (grey line). (f) Circumferential strain throughout the cardiac cycle in a representative dog at baseline (black line) and after 6 weeks of high-fat feeding with salmon oil (grey line). (g) Left ventricular twisting pattern (torsion) throughout one cardiac cycle in a representative dog at baseline (black line) and after 6 weeks of high-fat feeding with salmon oil (grey line). (h) Circumferential strain throughout the cardiac cycle in a representative dog at baseline (black line) and after 6 weeks of high-fat feeding with lard (grey line). Arrows show the peak circumferential strain. (i) Left ventricular twisting pattern (torsion) throughout one cardiac cycle in a representative dog at baseline (black line) and after 6 weeks of high-fat feeding with lard (grey line). Arrows show the peak torsion. Dot plots represent the effects of diet on (j) peak circumferential strain and (k) peak torsion. Data are reported as the percentage change (% Δ) from baseline level (BL). The horizontal black lines indicate the mean. *p<0.05 for diet vs baseline, effect of condition. Circ, circumferential