Table 1. Baseline metabolic, hemodynamic and left ventricular data.
Variable | Control (n=6) | Lard (n=12) | Salmon oil (n=8) |
---|---|---|---|
Metabolic indices | |||
Weight (kg) | 29.5±0.5 | 31.5±0.6 | 31.7±1.1 |
Fasting glucose (mmol/l) | 5.3±0.2 | 5.3±0.1 | 5.3±0.1 |
Fasting insulin (pmol/l) | 40.6±11.0 | 50.4±7.7 | 34.6±6.8 |
SI ([mU/l]−1 min−1) | 8.4±1.1 | 5.3±0.5 | 8.3±1.2 |
AIRg (mU/l × min) | 398.8±28.3 | 501.6±48.8 | 519.2±64.0 |
MRI fat compartmentalisation | |||
Total body (cm3) | 744.5±22.5 | 834.9±32.5 | 775.8±25.2 |
Visceral fat depot (cm3) | 75.5±8.1 | 102.7±10.7 | 72.7±9.3 |
Subcutaneous fat depot (cm3) | 56.9±6.4 | 90.0±9.6 | 53.4±5.83 |
Lean mass (cm3) | 612.2±13.4 | 642.2±21.5 | 651.6±15.6 |
Hemodynamics | |||
Systolic BP (mmHg) | 83±3 | 83±3 | 81±3 |
Diastolic BP (mmHg) | 36 ±3 | 37±3 | 36±2 |
Heart rate (beats/min) | 86±3 | 85±3 | 83±5 |
Left ventricular morphology and global function | |||
End-diastolic volume (ml) | 97.0±5.5 | 99.6±4.9 | 104.8±5.6 |
Mass (g) | 85.5±7.6 | 88.2±3.4 | 95.2±5.1 |
Concentricity (g/ml) | 0.88±0.04 | 0.89±0.02 | 0.92±0.06 |
Ejection fraction (%) | 44±2 | 43±2 | 43±3 |
Circumferential strain and ventricular torsion | |||
Peak circumferential strain (%) | −11.8±0.7 | −11.6±0.7 | −11.4±0.7 |
Peak systolic strain rate (%/s) | −95.2±5.7 | −90.5±5.5 | −90.7±2.6 |
Peak diastolic strain rate (%/s) | 127.3±10.2 | 116.3±7.7 | 114.1±7.2 |
Peak torsion (°/cm) | 2.3±0.2 | 1.9±0.2 | 1.9±0.2 |
Peak twisting rate (°/s) | 54.9±3.0 | 51.5±4.9 | 50.1±3.9 |
Peak untwisting rate (°/s) | −66.7±9.2 | −70.6±8.5 | −59.1±6.6 |
Myocardial triacylglycerola (%fat/H2O) | 0.13±0.07 | 0.15±0.04 | 0.07±0.05 |
Data are mean ± SEM
By MRS
To convert SI values to SI units, multiply by 0.167. To convert AIRg to SI units, multiply by 6