Table 2.
Prognostic groups | Group prognostic variables | Median survival (months) |
95% CI (months) |
|
---|---|---|---|---|
CALGB index | Group 1 | PS =0, age <49 years | 13.9 | 11.1–31.4 |
PS =0, age ≥49 years, Hgb ≥14.6 | ||||
Group 2 | PS =1/2, WBC <8.7, no chest pain | 9.5 | 6.9–14.7 | |
Group 3 | PS =0, age ≥49 years, Hgb <14.6 | 9.2 | 75–10.5 | |
PS =1/2, WBC count <15.6, chest pain, no weight loss, Hgb ≥12.3 | ||||
PS =1/2, WBC 9.8–15.5, chest pain, weight loss, Hgb ≥11.2 | ||||
Group 4 | PS =1/2, WBC 8.7–15.5, no chest pain | 6.5 | 3.7–9.4 | |
Group 5 | PS =1/2, WBC <15.6, chest pain, no weight loss, Hgb <12.3 | 4.4 | 3.4–5.1 | |
PS =1/2, WBC 9.8–15.5, chest pain, weight loss, Hgb <11.2 | ||||
PS =1/2, WBC <9.8, chest pain, weight loss | ||||
Group 6 | PS =1/2, WBC ≥15.6 | 1.4 | 0.5–3.6 |
Note: Adapted from Chest, 113/3, Herndon JE, Green MR, Chahinian AP, et a, Factors predictive of survival among 337 patients with mesothelioma treated between 1984 and 1994 by the Cancer and Leukemia Group B, 723–731, Copyright (1998), with permission from Elsevier.32
Abbreviations: CALGB, Cancer and Leukemia Group B; CI, confidence interval; PS, Eastern Cooperative Oncology Group performance status; Hgb, hemoglobin (g/dL); WBC, white blood cell (109/L).