Table S1.
Laboratory data at the start of the first-, second-, and third-line chemotherapies
| Variables | Mean ± SD
|
||
|---|---|---|---|
| First-line chemotherapy (N=118) |
Second-line chemotherapy (N=65) |
Third-line chemotherapy (N=31) |
|
| Leukocyte (cells/μL) | 7,535±2,743 | 6,448±2,088 | 6,319±2,457 |
| Neutrophil (cells/μL) | 5,174±2,505 | 4,211±1,875 | 4,348±1,690 |
| Lymphocyte (cells/μL) | 1,663±675 | 1,545±610 | 1,321±516 |
| Monocyte (cells/μL) | 487±213 | 500±176 | 487±195 |
| Hemoglobin (g/dL) | 12.9±1.9 | 12.0±2.0 | 11.5±1.9 |
| Platelet (×103 cells/μL) | 243±93 | 217±75 | 222±91 |
| Serum sodium (mEq/L) | 138.6±4.5 | 138.8±3.9 | 138.9±3.6 |
| Lactate dehydrogenase (IU/L) | 316±177 | 320±241 | 403±418 |
| Alkaline phosphatase (IU/L) | 305±216 | 288±336 | 277±147 |
| C-reactive protein (mg/dL) | 2.48±4.46 | 1.42±3.33 | 2.35±3.80 |
| Neutrophil-to-lymphocyte ratio | 3.83±3.21 | 3.27±2.17 | 5.80±14.16 |
| Platelet-to-lymphocyte ratio | 177.4±128.1 | 168.2±108.1 | 240.3±342.6 |
| Lymphocyte-to-monocyte ratio | 3.86±2.03 | 3.50±1.89 | 3.19±1.80 |
Abbreviation: SD, standard deviation