Table S5.
Treatment response and discontinuation
| Response and discontinuation | First-line | Second-line | Third-line |
|---|---|---|---|
|
| |||
| N=103 | N=63 | N=32 | |
| Response | |||
| Complete response, N | 2 | 0 | 0 |
| Partial response, N | 42 | 4 | 1 |
| Stable disease, N | 22 | 24 | 8 |
| Progressive disease, N | 28 | 27 | 19 |
| Not evaluated, N | 9 | 8 | 4 |
| Overall response rate, % | 42.7 | 6.3 | 3.1 |
| Disease control rate, % | 64.1 | 44.4 | 28.1 |
| Reasons of discontinuation, N | |||
| Progressive disease | 34 | 34 | 17 |
| Completion of four to six courses | 25 | 7 | 2 |
| Adverse effects | 18 | 8 | 1 |
| Patient refusals | 2 | 2 | 0 |
| Transfer to other hospitals | 1 | 0 | 1 |
| Cancer-related deteriorated condition | 8 | 6 | 6 |
| Comorbidity-related deteriorated condition | 15 | 5 | 4 |
| Ongoing | 0 | 0 | 1 |