Table 1. Gene numbers of GST, CYP and CCE superfamilies from R. prolixus genome and from T. dimidiata, T. infestans and T. pallidipennis transcriptomes in comparison with other insect species.
Numbers were derived from Claudianos et al. (2006), Feyereisen et al. (2006 and 2012), Oakeshott et al. (2010), Ramsey et al. (2010), Shi et al. (2012) and http://drnelson.uthsc.edu/aphid.htm. (*) Shi et al. (2012) found one Epsilon GST in A. pisum while Ramsey et al. (2010) did not find any Epsilon GST.
| Superfamily | Class/Clade | R. prolixus | T. dimidiata | T. infestans | T. pallidipennis | D. melanogaster | An. gambiae | A. mellifera | A. pisum |
|---|---|---|---|---|---|---|---|---|---|
| CYPs | Mitochondrial | 8 | 3 | 6 | 6 | 11 | 9 | 6 | 8 |
| Families | CYP301, 302, 314, | CYP301, | CYP301, 302, | CYP301, 302, | CYP12,49,301, | CYP12,49,301, | CYP301, 302, | CYP301, 302, | |
| 315, 394, 404 | 394, 404 | 315, 404 | 315, 394, 404 | 302, 314,315 | 302, 314,315 | 314, 315, 334 | 314, 315, 353 | ||
| CYP2 | 7 | 6 | 1 | 8 | 7 | 10 | 8 | 10 | |
| Families | CYP15, 18, 303, 305 | CYP15, 306, 307 | CYP303 | CYP15, 18, 303 | CYP18, 303–307 | CYP15, 303–307 | CYP15, 18, 303, | CYP15, 18, 303, | |
| 306, 307 | 306, 307 | 305–307, 342, 343 | 305–307 | ||||||
| CYP3 | 55 | 59 | 65 | 69 | 36 | 40 | 28 | 23 | |
| Families | CYP6, 395, | CYP6, 395, | CYP6, 395, | CYP6, 395, | CYP6, 9, 28, | CYP6, 9, 329 | CYP6, 9, 336 | CYP6 | |
| 3084–3092, 3096 | 3084–3092 | 3084–3091 | 3084–3092 | 308–310, 317 | |||||
| CYP4 | 49 | 19 | 22 | 30 | 32 | 46 | 4 | 23 | |
| Families | CYP4, 3093 | CYP4, 3093 | CYP4, 3093 | CYP4, 3093 | CYP4, 311–313, | CYP4, 325 | CYP4 | CYP4, 380 | |
| 316, 318 | |||||||||
| Subtotal | 119 | 87 | 94 | 113 | 88 | 105 | 46 | 64 | |
| CCEs | Dietary class | ||||||||
| A clade | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 5 | |
| B clade | 0 | 0 | 0 | 0 | 13 | 16 | 3 | 0 | |
| C clade | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Pheromone/hormone processing class | |||||||||
| D clade | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 0 | |
| E clade | 40 | 25 | 18 | 17 | 2 | 4 | 2 | 18 | |
| F clade | 0 | 0 | 0 | 0 | 3 | 6 | 2 | 0 | |
| G clade | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | |
| Neuro/developmental class | |||||||||
| H clade | 2 | 1 | 0 | 1 | 5 | 10 | 1 | 0 | |
| I clade | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | |
| J clade | 2 | 0 | 1 | 0 | 1 | 2 | 2 | 2 | |
| K clade | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | |
| L clade | 13 | 1 | 0 | 0 | 4 | 5 | 5 | 3 | |
| M clade | 2 | 0 | 0 | 0 | 2 | 2 | 1 | 0 | |
| Subtotal | 61 | 27 | 19 | 18 | 35 | 51 | 24 | 30 | |
| GSTs | Delta | 1 | 1 | 1 | 1 | 11 | 17 | 2 | 16 |
| Epsilon | 0 | 0 | 0 | 0 | 14 | 8 | 0 | 1 (0) * | |
| Omega | 1 | 2 | 0 | 1 | 4 | 1 | 2 | 2 | |
| Sigma | 7 | 13 | 9 | 5 | 1 | 1 | 4 | 6 | |
| Theta | 3 | 2 | 2 | 1 | 4 | 2 | 1 | 2 | |
| Zeta | 1 | 1 | 0 | 1 | 2 | 1 | 1 | 0 | |
| Microsomal | 1 | 3 | 2 | 2 | 3 | 3 | 2 | 2 | |
| Unknown | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 3 | |
| Subtotal | 14 | 22 | 14 | 11 | 40 | 35 | 13 | 32 | |
| Total | 194 | 136 | 127 | 142 | 163 | 191 | 83 | 126 |