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. 2017 Feb 15;12(2):e0172263. doi: 10.1371/journal.pone.0172263

Fig 4. The competition of heparin for the interaction between the DS and TG2.

Fig 4

The DS that was immobilized onto sensor disc was exposed to 150 nM of TG2 without heparin (control) or with indicated amounts of heparin, as described in Materials and methods. (A) Representative sensorgrams that show the interaction between the DS and TG2 in the presence of heparin. (B) The interference of heparin in the DS-TG2 interaction was estimated as reduction in the surface plasmon resonance (SPR) signal. The results (the observed SPR response) are means ± S.D. of at least 3 independent experiments. a–statistically significant differences compared to the binding without heparin (p ≤ 0.05).