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. 2017 Feb 15;12(2):e0172131. doi: 10.1371/journal.pone.0172131

Table 2. Table of pathways and Gene Ontology (GO) biological processes associated with miR-19a, -20a, -185 and -374b.

KEGG Pathway Enrichment Score GO Biological Process Enrichment Score
Axon guidance 24.08 cell adhesion 22.90
Wnt signaling pathway 23.66 blood coagulation 14.72
Pathways in cancer 23.50 angiogenesis 13.83
p53 signaling pathway 21.19 canonical Wnt receptor signaling pathway 8.99
Ubiquitin mediated proteolysis 20.44 platelet activation 7.46
Transcriptional misregulation in cancer 20.10 wound healing 7.40
TGF-beta signaling pathway 20.08 positive regulation of angiogenesis 5.74
Endocytosis 19.75 Wnt receptor signaling pathway, calcium modulating pathway 5.57
Melanogenesis 18.83 vascular endothelial growth factor receptor signaling pathway 5.44
Gap junction 17.13 negative regulation of canonical Wnt receptor signaling pathway 5.03
GnRH signaling pathway 16.65 Wnt receptor signaling pathway 4.55
Prostate cancer 15.97 Notch signaling pathway 4.51
MAPK signaling pathway 15.18 cell-matrix adhesion 4.35
HTLV-I infection 15.18 negative regulation of cell adhesion 3.95
Salivary secretion 13.52 transforming growth factor beta receptor signaling pathway 3.95
Calcium signaling pathway 13.35 regulation of cell adhesion 3.65
ABC transporters 13.09 positive regulation of endothelial cell migration 3.60
Melanoma 12.52 positive regulation of vasoconstriction 3.60
Regulation of actin cytoskeleton 12.17 positive regulation of endothelial cell proliferation 3.37
ErbB signaling pathway 12.17 blood vessel development 3.17