Table 3. Predicted targets of miR-19a, -20a, -185 and -374b in complement and coagulation cascade.
hsa-miRNA | Predicted targets |
---|---|
miR-19a | AT3, CD46, CD55, F5, F13, PAI-1, TF, TFPI and PLAU |
miR-20a | CD46 and PAI-1 |
miR-185 | CD46, F7, F8, F11, F13 and PLAT |
miR-374b | CD46, CD55, F5, PAI-2 and TFPI |
AT3: Anti-thrombin III. CD46: Cluster of differentiation 46. CD55: Cluster of differentiation 55. F5: Factor V. F7: Factor VII. F8: Factor VIII. F11: Factor XI. F13: Factor XIII. PAI-1: Plasminogen activator inhibitor-1. PAI-2: Plasminogen activator inhibitor-2. PLAT: tissue plasminogen activator. PLAU: urokinase-type plasminogen activator. TF: Tissue factor. TFPI: Tissue factor pathway inhibitor.