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. 2017 Feb 15;12(2):e0172174. doi: 10.1371/journal.pone.0172174

Fig 5. The effect of pravastatin on the feto-placental pressure.

Fig 5

A. feto-placental pressure was monitored and recorded throughout the experiment and remained in the range of 25–40 mmHg. Cntl: n = 8; PraM: n = 11; B. Feto-placental vasoconstriction was induced by bolus injections of angiotensin-II as described in the "materials and methods" section. The cotyledons were allowed to recover between injections. Angiotensin-II-induced vasoconstriction was normalized to the baseline vasoconstriction and expressed as relative values of contraction. C. The concentrations of NO (normalized to gram of perfused cotyledon) in samples collected from the fetal reservoir following the experimental protocol as described in details in the "materials and methods" section. Cntl: n = 4; PraM: n = 3.