Table 1. Descriptive Statistics.
Primary sample: those with valid MetS severity scores, fasting insulin and adiponectin at the PFS Visit (n = 711). From those 711 participants, the LRC column provides data at the LRC (child) visit for the n = 595 participants < 20 years old and who had valid MetS severity scores at the time. The PHU column provides data on those 417 individuals from the 711 who were followed up during the 2010–2014 period.
| Primary Analysis Sample (n = 711) | |||
|---|---|---|---|
|
| |||
| LRC Visit 1973–1976 |
PFS Visit 1998–2003 |
PHU Contact 2010–2014 |
|
| N | 595 | 711 | 417 |
| Mean (SD): | |||
| Age (years) | 12.9 (3.3) | 39.5 (4.7) | 50.9 (4.9) |
| BMI (kg/m2) | 20.0 (4.3) | 28.8 (6.8) | -- |
| Waist (cm) | -- | 97.5 (16.9) | -- |
| Glucose (mg/dL) | 85.4 (8.2) | 90.6 (27.7) | -- |
| HDL-C (mgl/dL) | 54.5 (12.1) | 45.3 (14.3) | -- |
| Triglycerides (mg/dL) | 74.7 (38.3) | 136.7 (115.5) | -- |
| Systolic blood pressure (mm Hg) | 102.8 (12.7) | 121.0 (15.2) | -- |
| Diastolic blood pressure (mm Hg) | 63.1 (11.3) | 79.8 (11.1) | -- |
| Metabolic syndrome severity score (z-score) | −0.5 (0.8) | 0.1 (1.1) | -- |
| Fasting insulin | -- | 10.9 (9.0) | -- |
| Adiponectin | 10.4 (6.8) | -- | |
| Frequency (Percent): | |||
| Male | 259 (43.5%) | 316 (44.4%) | 174 (41.7%) |
| White | 418 (70.3%) | 502 (70.6%) | 321 (77.0%) |
| Overweight* | 71 (11.9%) | 231 (32.5%) | -- |
| Obese* | 57 (9.6%) | 247 (34.8%) | -- |
| Metabolic syndrome | 22 (3.7%) | 231 (32.5%) | -- |
| High Insulin (≥ 16) | -- | 132 (18.6%) | -- |
|
| |||
| T2DM** | -- | 37 (5.4%) | 60 (14.4%) |
|
| |||
| Myocardial Infarction** | -- | 6 (0.9%) | 15 (3.7%) |
| Stroke** | -- | 3 (0.4%) | 11 (2.8%) |
| Angioplasty, Stent, Bypass, or other Heart Surgery** | -- | 1 (0.1%) | 14 (3.5%) |
|
| |||
| Cardiovascular Disease** | 10 (1.4%) | 29 (7.1%) | |
|
| |||
| Deceased** | -- | 0 | 7 (1.7%) |
*
Overweight = BMI ≥ 85th percentile for LRC, ≥ 25 for PFS; Obese = BMI ≥ 95th percentile for LRC, ≥ 30 for PFS
**
Cumulative frequencies by the designated visit