Table 2. Relationship between MetS severity and levels of fasting insulin and adiponectin.

Linear regression of Ln(Insulin) and Ln(Adiponectin) measured at PFS as a function of MetS or MetS Severity during childhood (LRC, 1973–1976) and adulthood (PFS 1998–2003) (only using the n = 595 participants with LRC data).

	Ln(Fasting Insulin)		Ln(Adiponectin)
	Parameter Estimate (SE)	p-value	Parameter Estimate (SE)	p-value
Baseline (LRC) Models
Model 1: Pediatric ATP-III MetS at LRC
Intercept	2.10 (0.03)	< 0.001	2.17 (0.02)	< 0.001
MetS at LRC	0.41 (0.15)	0.007	−0.24 (0.13)	0.069
R-squared	0.01		0.01
Model 2: MetS severity at LRC
Intercept	2.23 (0.03)	< 0.001	2.13 (0.03)	< 0.001
MetS z-score at LRC	0.24 (0.04)	< 0.001	−0.08 (0.03)	0.010
R-squared	0.07		0.01
PFS-Only Models
Model 3: ATP-III MetS at PFS
Intercept	1.88 (0.03)	< 0.001	2.32 (0.03)	< 0.001
MetS at PFS	0.79 (0.05)	< 0.001	−0.51 (0.05)	< 0.001
R-squared	0.28		0.15
Model 4: MetS severity at PFS
Intercept	2.09 (0.02)	< 0.001	2.19 (0.02)	< 0.001
MetS z-score at PFS	0.38 (0.02)	< 0.001	−0.24 (0.02)	< 0.001
R-squared	0.38		0.20
Models over both Time Periods
Model 5: MetS severity over time
Intercept	2.09 (0.03)	< 0.001	2.23 (0.03)	< 0.001
MetS z-score at LRC	0.38 (0.03)	< 0.001	−0.18 (0.03)	< 0.001
Change in MetS z-score (PFS-LRC)	0.38 (0.02)	< 0.001	−0.27 (0.02)	< 0.001
R-squared	0.38		0.21