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. Author manuscript; available in PMC: 2017 Feb 15.
Published in final edited form as: J Huntingtons Dis. 2016 Oct 1;5(3):217–237. doi: 10.3233/JHD-160205

Fig. 1.

Fig. 1

A brief overview of involvement of reactive oxygen species in multiple physiological and pathological functions as signaling molecules. Recent findings have placed ROS as very critical signaling factors which are involved in regulating not only pathological functions but also in a host of functions necessary for normal cellular function. Therefore, a very careful attention is needed before considering antioxidants as therapeutic options for Huntington’s disease.