Table 3. Bivariate correlations between expression of Vitamin D Receptor (VDR) and other skeletal muscle target genes.
Data are Spearman correlation coefficients (rho)), with 95% confidence intervals (CI) and p values in brackets).
| VDR Expression | |||
|---|---|---|---|
| Gene | rho | 95% CI | p-value |
| mTOR | -0.18 | -0.44–0.10 | 0.20 |
| Atrogin1 | -0.24 | -0.49–0.04 | 0.08 |
| P300 | 0.24 | -0.04–0.49 | 0.08 |
| MuRF1 | -0.23 | -0.48–0.05 | 0.10 |
| Calpain1 | -0.26 | -0.51–0.02 | 0.06 |
| Calpain2 | -0.18 | -0.44–0.11 | 0.21 |
| USP19 | -0.27 | -0.51–0.01 | 0.05 |
| ATF-4 | -0.15 | -0.42–0.14 | 0.28 |
| Caspase3 | 0.15 | -0.14–0.42 | 0.28 |
| eIF4BP1 | -0.23 | -0.49–0.05 | 0.10 |
| FOXO1 | -0.22 | -0.48–0.06 | 0.12 |
| FOXO3 | -0.20 | -0.45–0.09 | 0.16 |
| MYH1 | -0.24 | -0.49–0.04 | 0.09 |
| MYH2 | -0.36 | -0.58–-0.08 | 0.009 |
| MYH4 | -0.21 | -0.47–0.08 | 0.13 |
| Myogenin | -0.06 | -0.33–0.23 | 0.69 |
| SIRT1 | -0.22 | -0.47–0.07 | 0.12 |
| SIRT3 | -0.30 | -0.54–-0.02 | 0.03 |
| Myostatin | -0.32 | -0.55–-0.04 | 0.02 |
| SMAD2 | 0.32 | 0.04–0.55 | 0.02 |
| SMAD3 | -0.25 | -0.50–0.03 | 0.07 |
| SMAD4 | -0.33 | -0.56–-0.05 | 0.02 |
| SMAD7 | 0.33 | 0.06–0.56 | 0.02 |
| ACVR2A | -0.33 | -0.56–-0.05 | 0.02 |
| ACVR2B | -0.25 | -0.50–0.03 | 0.07 |
| RELA | -0.22 | -0.47–0.06 | 0.11 |
| RELB | -0.01 | -0.29–0.27 | 0.95 |
| IL6 | 0.07 | -0.21–0.35 | 0.59 |
| IL1B | 0.17 | -0.12–0.43 | 0.24 |
| NFKB1 | -0.21 | -0.46–0.08 | 0.15 |
| INSR | -0.23 | -0.48–0.05 | 0.11 |
| IRS1 | -0.34 | -0.57–-0.07 | 0.01 |
| AKT1 | -0.18 | -0.44–0.11 | 0.21 |
| GSK3B | -0.18 | -0.44–0.11 | 0.21 |
| DDIT4 | -0.36 | -0.59–-0.09 | 0.009 |
| HSD11B1 | -0.15 | -0.41–0.14 | 0.30 |
| HSD11B2 | -0.06 | -0.34–0.22 | 0.68 |
| H6PD | -0.27 | -0.51–0.02 | 0.06 |
| HSP90AA1 | -0.21 | -0.46–0.08 | 0.14 |
| HSP90B1 | -0.05 | -0.33–0.23 | 0.74 |
| GHR | -0.30 | -0.54–-0.02 | 0.03 |
| GHSR | 0.25 | -0.04–0.50 | 0.08 |
| IGF1 | 0.02 | -0.27–0.30 | 0.90 |
| HIF1A | -0.04 | -0.32–0.25 | 0.79 |
| EIF6 | -0.11 | -0.39–0.17 | 0.42 |
| EIF2B1 | -0.21 | -0.47–0.07 | 0.14 |
| PDK4 | -0.10 | -0.37–0.19 | 0.50 |
| IGF1R | -0.25 | -0.49–0.04 | 0.08 |
| GADD45A | -0.15 | -0.41–0.14 | 0.30 |
| ACACA | -0.17 | -0.44–0.12 | 0.22 |
| AR | -0.23 | -0.48–0.06 | 0.11 |
| CD36 | -0.04 | -0.32–0.25 | 0.80 |
| CDKN1A | 0.15 | -0.13–0.42 | 0.28 |
| CEBPB | -0.31 | -0.55–-0.03 | 0.03 |
| CRYAB | -0.14 | -0.41–0.15 | 0.33 |
| CYCS | -0.31 | -0.55–-0.03 | 0.02 |
| GLUL | -0.36 | -0.58–-0.08 | 0.01 |
| HSL | -0.19 | -0.45–0.10 | 0.18 |
| LPL | 0.03 | -0.26–0.31 | 0.86 |
| MYCL1 | -0.18 | -0.44–0.11 | 0.21 |
| MYF5 | -0.13 | -0.40–0.16 | 0.35 |
| NR3C1 | 0.17 | -0.12–0.42 | 0.25 |
| PPARD | -0.21 | -0.47–0.07 | 0.13 |
| PPARG | 0.01 | -0.27–0.29 | 0.93 |
| PPARGC1A | -0.34 | -0.57–-0.06 | 0.02 |
| PPP3R2 | 0.28 | -0.00–0.51 | 0.05 |
| PSMA2 | -0.03 | -0.31–0.25 | 0.86 |
| PSMC1 | -0.24 | -0.49–0.05 | 0.09 |
| PSMC2 | -0.24 | -0.49–0.05 | 0.09 |
| PSMC4 | -0.27 | -0.52–0.01 | 0.05 |
| PSMC5 | -0.34 | -0.57–-0.07 | 0.01 |
| PSMC6 | -0.20 | -0.45–0.09 | 0.17 |
| PSMD1 | -0.26 | -0.51–0.03 | 0.07 |
| PSMD11 | -0.27 | -0.52–0.01 | 0.05 |
| PSMD12 | -0.24 | -0.49–0.05 | 0.10 |
| PSMD14 | -0.30 | -0.54–-0.02 | 0.03 |
| PSMD2 | -0.29 | -0.53–-0.01 | 0.04 |
| PSMD3 | -0.20 | -0.45–0.09 | 0.17 |
| PSMD4 | 0.05 | -0.24–0.33 | 0.74 |
| PSMD6 | -0.26 | -0.50–0.03 | 0.07 |
| PSMD7 | -0.25 | -0.50–0.03 | 0.07 |
| RPS6KB1 | -0.31 | -0.54–-0.03 | 0.03 |
| RXRG | -0.30 | -0.54–-0.01 | 0.03 |
| SLC2A4 | -0.27 | -0.51–0.02 | 0.06 |
| SOCSS3 | -0.08 | -0.36–0.21 | 0.58 |
| SOD1 | -0.30 | -0.54–-0.01 | 0.03 |
| SREBF1 | -0.22 | -0.48–0.07 | 0.12 |
| TGFB1 | -0.13 | -0.40–0.16 | 0.37 |
| TNFA | -0.02 | -0.30–0.26 | 0.90 |
| TRIM54 | -0.28 | -0.52–0.00 | 0.04 |