Table 3. Patient management.
| Variable | Adults N = 20 |
Pediatrics N = 31 |
|
|---|---|---|---|
| Antimicrobials received during admission | |||
| Antibiotic, n (%) | 16 (80.0%) | 26 (83.9%) | |
| Amoxicillin | 1 (5.0%) | 1 (3.2%) | |
| Ampicillin | 0 (0.0%) | 8 (25.8%) | |
| Ceftriaxone | 9 (45.0%) | 9 (29.0%) | |
| Chloramphenicol | 3 (15.0%) | 12 (38.7%) | |
| Ciprofloxacin | 1 (5.0%) | 0 (0.0%) | |
| Dicloxacillin | 1 (5.0%) | 0 (0.0%) | |
| Doxycycline | 1 (5.0%) | 0 (0.0%) | |
| Erythromycin | 0 (0.0%) | 1 (3.2%) | |
| Gentamicin | 2 (10.0%) | 9 (29.0%) | |
| Penicillin G | 0 (0.0%) | 1 (3.2%) | |
| Trimethoprim-Sulfamethoxazole | 3 (15.0%) | 0 (0.0%) | |
| Antihelminth, n (%) | 1 (5.0%) | 2 (6.5%) | |
| Albendazole | 1 (5.0%) | 1 (3.2%) | |
| Mebendazole | 0 (0.0%) | 1 (3.2%) | |
| Antimalarial, n (%) | 8 (40.0%) | 8 (25.0%) | |
| Artemether | 5 (25.0%) | 8 (25.8%) | |
| Quinine | 5 (25.0%) | 0 (0.0%) | |
| Antiviral, n (%) | 0 (0.0%) | 0 (0.0%) | |
| Oxygen support if hypoxic, n (%)a | |||
| SpO2 < 94% | 4/9 (44.4%) | 9/11 (81.2%) | |
| SpO2 < 90% | 3/3 (100.0%) | 5/5 (100%) | |
| IV fluid bolus if hypoperfused, n (%)b | |||
| Mild, venous lactate > 2 and ≤4 mmol/L | 3/7 (42.9%) | 8/14 (57.1%) | |
| Severe, venous lactate > 4 mmol/L | 4/8 (50.0%) | 3/5 (60.0%) | |
aIn first 24hr of admission.
bMild hypoperfusion defined as systolic blood pressure < 90mmHg (in adults) or venous lactate > 2 and ≤ 4 mmol/L in the first 24hr of admission. Severe hypoperfusion defined as systolic blood pressure < 70 mmHg (in adults) or venous lactate > 4 mmol/L in the first 24hr of admission. Fluid bolus defined as ≥ 2L isotonic crystalloid in first 24hr in adults and ≥ 20 mL/kg isotonic crystalloid in the first 24hr in pediatrics.