Table 2. Summary of risk estimates.
Manitoba, Canada | Denmark Chlamydia Study | UK-based POPI-RCT | ||
---|---|---|---|---|
Deferred screening | Screened | |||
Prevalence of chlamydia (95% CI) | 5.48% (5.31–5.65) | 4.32% (3.65–4.99) | 5.93% (4.63–7.23) | 5.42% (4.17–6.68) |
Observed rate of PID per 100,000 women by 12-months | 2086.04 | 890.16 | 1598.96~ | 1346.07~ |
Incidence of PID in chlamydia positive (95% CI) | 5.27% (4.59–6.00) | 1.28% (1.21–1.35) | 9.46% (2.79–16.13) | 1.59% (0.00–8.53) |
Incidence of PID in chlamydia-negative (95% CI) | 1.90% (1.80–2.00) | 0.67% (0.63–0.71) | 1.34% (0.91–1.91)* | |
Relative risk (95% CI) | 2.77 (2.41–3.20) | 1.92 (1.78–2.08) | 7.06 (3.21–15.55) | 1.19 (1.64–8.55) |
Attributable risk | 3.37 | 0.61 | 8.12 | 0.25 |
Attributable risk % | 63.95% | 48.01% | 85.84% | 15.63% |
Population excess fraction (95% CI) | 8.86% (7.15–10.75) | 3.84% (3.26–4.41) | 26.44% (11.57–46.32) | 0.99% (0.00–29.06) |
Crude number of cases attributed to baseline chlamydia in cohort of tested women (study size) | 134 (72,883) | 98 (286,223) | 6 (1270)** | 0.1 (1259)** |
Number of cases attributed to baseline chlamydia per 100,000 tested women | 184 | 34 | 484 | 13 |
~Data not available to allocate PID incidence in chlamydia-negative women to the two study arms therefore combined chlamydia-negative data used in calculation
*Data not available to calculate separately
**Assumption that incidence of PID in chlamydia-negative women is 1.34%.