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. Author manuscript; available in PMC: 2017 Feb 16.
Published in final edited form as: J Am Geriatr Soc. 2016 Dec 5;65(2):277–285. doi: 10.1111/jgs.14551

Table 3.

Results from multivariable linear regression models examining the cross sectional relation of HBA1c levels and dysglycemia categories to cognitive performance.

Model 1 Model 2 Model 3 Model 4
Beta SE p Beta SE p Beta SE p Beta SE p
Memory
HbA1c continuous −0.07 0.06 0.27 −0.06 0.05 0.28 −0.01 0.05 0.82 −0.02 0.05 0.69
Known Diabetes −0.15 0.09 0.11 −0.16 0.08 0.06 0.03 0.08 0.73 0.01 0.09 0.84
Undiagnosed diabetes −0.07 0.11 0.53 −0.07 0.11 0.50 0.10 0.10 0.31 0.11 0.11 0.29
Pre-diabetes −0.12 0.09 0.18 −0.09 0.08 0.26 −0.004 0.08 0.96 0.01 0.08 0.88
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Language
HbA1c continuous −0.11 0.05 0.02 −0.10 0.04 0.02 −0.02 0.03 0.46 −0.01 0.03 0.79
Known Diabetes −0.30 0.08 <0.0001 −0.31 0.07 <0.0001 −0.06 0.06 0.29 −0.04 0.06 0.54
Undiagnosed diabetes −0.22 0.09 0.02 −0.22 0.09 0.01 0.008 0.07 0.91 0.04 0.07 0.57
Pre-diabetes −0.11 0.07 0.15 −0.08 0.07 0.27 0.05 0.05 0.34 0.08 0.06 0.17
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Speed
HbA1c continuous −0.22 0.08 0.01 −0.20 0.08 0.01 −0.08 0.07 0.23 −0.09 0.07 0.23
Known Diabetes −0.44 0.14 0.002 −0.46 0.13 0.001 −0.21 0.12 0.10 −0.21 0.13 0.12
Undiagnosed diabetes −0.36 0.17 0.03 −0.34 0.16 0.03 −0.09 0.15 0.51 −0.11 0.15 0.45
Pre-diabetes −0.26 0.13 0.05 −0.22 0.13 .09 −0.02 0.12 0.83 −0.01 0.12 0.89
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Visuospatial
HbA1c continuous −0.09 0.04 0.04 −0.08 0.04 0.05 −0.01 0.03 0.63 −0.01 0.03 0.69
Known Diabetes −0.29 0.07 <0.0001 −0.30 0.07 <0.0001 −0.09 0.05 0.09 −0.09 0.06 0.14
Undiagnosed diabetes −0.22 0.08 0.02 −0.19 0.08 0.02 −0.008 0.06 0.91 −0.005 0.07 0.94
Pre-diabetes −0.15 0.07 0.02 −0.12 0.06 0.05 −0.008 0.05 0.87 0.004 0.05 0.94
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Model 1=crude; Model2=adjusted for age, sex; Model3= adjusted for age, sex, education, ethnic group, APOE; Model4= adjusted for age, sex, education, ethnic group, APOE-ε4; hypertension, smoking, Body Mass Index, High Density Lipoprotein.