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. Author manuscript; available in PMC: 2018 Feb 15.
Published in final edited form as: Bioconjug Chem. 2017 Jan 12;28(2):600–608. doi: 10.1021/acs.bioconjchem.6b00687

Figure 6. Pharmacokinetics, biodistribution and whole-body imaging of QD and 89Zr dual-labeled nanoparticles.

Figure 6

a, Blood circulation half-life and b, radioactivity biodistribution in selected tissues after intravenous administration of 89Zr-QD-BP (blue), 89Zr-QD-MC (green) and 89Zr-QD-NE (red) in mice bearing DU145 tumor. c–f, Whole-body imaging of mice intravenously injected with 89Zr-QD-BP at 24 h post-injection, showing MIP PET/CT fusion image (c), 3-D rendered PET/CT fusion image (d), QD-assisted CL imaging (e), and QD NIRF imaging (excitation 600 nm, emission 720 nm) (f).