. 2017 Feb 16;8:124. doi: 10.3389/fimmu.2017.00124

Table 2.

Repeated measurements at weekly time points.

	Time point (week)	Control/no stretch N = 12	Control/stretch N = 12	sclGvHD/no stretch N = 12	sclGvHD/stretch N = 12	p-Value (ANOVA)
Thickness Zone 1 (μm)	1	489.14 ± 13.97^a	488.06 ± 17.77^a	472.77 ± 16.30^ab	462.60 ± 11.35^b	0.040
	2	486.50 ± 9.82^a	485.15 ± 14.84^a	606.08 ± 14.22^b	599.06 ± 15.76^b	<0.001
	3	491.67 ± 9.27^a	479.52 ± 16.30^a	554.85 ± 16.26^b	503.19 ± 13.50^a	<0.001
	4	473.29 ± 17.92	476.96 ± 18.47^a	463.04 ± 13.93^ab	448.40 ± 16.94^b	0.037
Thickness Zone 2 (μm)	1	327.29 ± 11.39^a	345.52 ± 16.10^a	327.54 ± 16.64^a	320.46 ± 9.75^a	0.060
	2	319.10 ± 9.27^a	320.38 ± 12.27^a	410.23 ± 11.06^b	410.75 ± 16.69^b	<0.001
	3	319.25 ± 12.75^a	324.75 ± 14.43^a	395.77 ± 15.91^b	355.75 ± 13.05^a	<0.001
	4	312.06 ± 17.48^a	326.40 ± 17.42^a	313.35 ± 12.91^a	309.46 ± 15.46^a	0.120
Thickness Zone 3 (μm)	1	161.17 ± 6.37^a	142.54 ± 5.50^b	145.23 ± 2.71^b	142.15 ± 4.79^b	0.040
	2	167.40 ± 4.46^a	164.77 ± 4.20^a	195.85 ± 8.38^b	188.31 ± 6.27^b	<0.001
	3	172.42 ± 7.61^a	154.77 ± 3.60^b	159.08 ± 4.98^ab	147.44 ± 4.44^b	0.011
	4	161.23 ± 3.70^a	150.56 ± 3.78^ab	149.69 ± 5.77^ab	138.94 ± 5.50^b	0.037
Cumulative displacement (μm)	1	429.98 ± 44.92^a	432.64 ± 28.59^a	381.75 ± 34.95^a	364.27 ± 42.33^a	0.238
	2	422.20 ± 52.54^a	464.33 ± 29.66^a	416.84 ± 37.61^a	455.58 ± 49.48^a	0.629
	3	456.93 ± 35.99^a	444.10 ± 33.98^a	344.88 ± 31.90^b	430.00 ± 30.34^a	0.037
	4	457.39 ± 33.13^ab	473.83 ± 23.88^a	331.28 ± 38.32^c	388.45 ± 22.28^bc	0.003
Clinical score	1	N/A	N/A	0.88 ± 0.09^b	0.88 ± 0.12^b	0.961
	2	N/A	N/A	0.04 ± 0.04^b	0.13 ± 0.09^b	0.864
	3	N/A	N/A	1.26 ± 0.32^b	1.50 ± 0.36^b	0.524
	4	N/A	N/A	2.22 ± 0.30^b	1.94 ± 0.34^b	0.378
Weight (g)	1	26.40 ± 0.55^a	26.10 ± 0.86^a	20.30 ± 0.58^b	20.17 ± 0.40^b	<0.001
	2	26.90 ± 0.58^a	26.46 ± 0.73^a	24.13 ± 0.44^b	24.26 ± 0.38^b	0.001
	3	27.06 ± 0.48^a	26.22 ± 0.63^a	22.83 ± 0.57^b	23.30 ± 0.45^b	<0.001
	4	27.13 ± 0.51^a	26.53 ± 0.70^a	21.53 ± 0.59^b	22.41 ± 0.48^b	<0.001

Results are expressed as mean ± SE. Means for experimental conditions within each time point.

Not sharing a common letter are significantly different (p < 0.05, Fisher’s protected LSD).