Figure 2.

Time between onset of clinical symptoms and diagnosis of antibody-associated encephalitis. Comparing patients with disease onset between 2007 and 2012 (A) versus 2013 to 2016 (B), the delay from symptom onset to the diagnosis of autoimmune encephalitis (light colors) has been reduced within the last years, likely due to increased awareness (please note the different y-axes). Applying the “red flag” criteria to the same patients by reanalyzing medical records resulted in a marked hypothetical reduction of the delay until antibody testing and encephalitis diagnosis (dark colors).