Figure 4.
miR-372-3p target prediction and potential miR-372-3p targets. (a) Cumulative distribution of mRNA level fold changes upon treatment with miR-372-3p mimic, calculated for four different mRNA subsets: mRNAs predicted as targets of miR-372-3p by more than four different target prediction algorithms; three to four algorithms; one to two algorithms or no algorithms. (b) Cumulative distribution of protein-level fold changes upon treatment with miR-372-3p mimic, otherwise same as in (a). (c) Venn diagram showing the overlap between mRNA level analysis of miR-372-3p effect, protein-level analysis of miR-372-3p effects and miR-372-3p target prediction analysis (targets predicted by more than four algorithms).