FIG 5.
Conserved synteny of the sigB locus in Gram-positive bacteria. The conserved synteny of the sigB locus identified in the Brochothrix genomes extends beyond the Listeriaceae family to other Gram-positive organisms. In both Brochothrix species, this region harbored predicted rsbU, rsbV, rsbW, and sigB genes. Large spacer regions between the rsbU and rsbV genes in S. aureus, B. subtilis, and L. monocytogenes contain σB-dependent promoters, which are likely not present in this intergenic region in Brochothrix species due to the short length of the respective spacer regions. Gray arrows depict a hypothetical protein-coding sequence.