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. 2017 Feb 15;83(5):e02786-16. doi: 10.1128/AEM.02786-16

TABLE 4.

Orthologs of L. monocytogenes virulence factors present in Brochothrix genomes according to functional categorya

Function Virulence factor Related gene Locus tag
B. thermosphacta DSM 20171 B. campestris DSM 4712
Adherence d-Alanine-phosphoribitol ligase dltA BFR34_01920 BCAMP_RS06480
Fibronectin-binding protein fbpA BFR34_07800 BCAMP_RS01735
Bile resistance Bile salt hydrolase bsh BFR34_01045 No hit
Enzyme Threonine phosphatase stp BFR34_07765 BCAMP_RS01770
Metalloprotease mpl No hit BCAMP_RS07830
Intracellular survival Lipoate protein ligase A1 lplA1 BFR34_04540 BCAMP_RS04420
Oligopeptide-binding protein oppA BFR34_01280 BCAMP_RS03095
Posttranslation chaperone prsA2 BFR34_04575 BCAMP_RS10760
Sugar uptake system hpt BFR34_09035 BCAMP_RS05315
Iron uptake Hemoglobin-binding protein hbp2 BFR34_05250 BCAMP_RS12765
Invasion Cell wall teichoic acid glycosylation protein gtcA BFR34_03990 BCAMP_RS09170
Promoting-entry protein lpeA BFR34_01515 BCAMP_RS03260
Peptidoglycan modification OatA oatA BFR34_04360 BCAMP_RS07115
Regulation Positive regulatory factor prfA BFR34_00370 No hit
LisR lisR BFR34_11190 BCAMP_RS07275
LisK lisK BFR34_11195 BCAMP_RS07280
VirR virR BFR34_09230 BCAMP_RS05130
VirS virS BFR34_09225 BCAMP_RS05135
Surface protein anchoring Diacylglyceryl transferase lgt BFR34_06385 BCAMP_RS05615
Specific signal peptidase II lspA BFR34_07940 BCAMP_RS09260
Sortase A srtA BFR34_10065 BCAMP_RS06070
Sortase B srtB BFR34_05235 BCAMP_RS10940
a

Orthologous genes with conserved synteny are highlighted in boldface type.