Table 2.
Laboratory Measurements and Risk Factors for the Metabolic Syndrome for Women With and Without Clinical Features of Polycystic Ovary Syndrome
| PCOS (n = 25) | No PCOS (n = 270) | p | |
|---|---|---|---|
| Cardiac risk factors, % | |||
| Hypertension | 48.0 | 63.3 | 0.29 |
| Diabetes mellitus | 24.0 | 32.2 | 0.66 |
| Dyslipidemia | 64.0 | 54.1 | 0.52 |
| Total cholesterol, mg/dL | 195.3 ± 36.6 | 197.8 ± 48.5 | 0.80 |
| LDL cholesterol, mg/dL | 110.1 ± 29.4 | 116.2 ± 42.0 | 0.57 |
| HDL cholesterol, mg/dL | 47.9 ± 10.3 | 52.5 ± 11.2 | 0.05 |
| <50 mg/dL, % | 64.0 | 42.4 | 0.06 |
| Triglycerides, mg/dL | 198.7 ± 136.5 | 148.7 ± 88.5 | 0.08 |
| >150 mg/dL, % | 52.0 | 42.4 | 0.40 |
| Body mass index, kg/m2 | 28.7 ± 5.9 | 30.0 ± 6.7 | 0.37 |
| ≥30 kg/m2, % | 36.0 | 40.6 | 0.83 |
| Waist/hip ratio | 0.89 ± 0.12 | 0.87 ± 0.12 | 0.58 |
| Range | 0.73–1.28 | 0.68–1.62 | |
| Waist circumference, inches | 38.5 ± 7.6 | 37.9 ± 7.2 | 0.70 |
| >35 inches, % | 68.0 | 60.2 | 0.52 |
| Blood pressure, mmHg | |||
| Systolic | 141.4 ± 19.9 | 140.4 ± 21.6 | 0.84 |
| Diastolic | 75.4 ± 12.5 | 76.7 ± 10.9 | 0.62 |
| Age at hypertension diagnosis, years, mean ± SD | 47.5 ± 11.6 | 50.5 ± 15.0 | 0.51 |
| Fasting glucose, mg/dL | 109.78 ± 46.5 | 121.4 ± 60.5 | 0.45 |
| >110 mg/dL, % | 12.5 | 34.6 | 0.10 |
| Age at diabetes diagnosis, years | 58.4 ± 9.6 | 51.5 ± 12.8 | 0.24 |
| Insulin resistance, HOMA | 3.07 ± 5.02 | 5.35 ± 8.24 | 0.12 |
| Fasting glucose >110 and triglycerides >150 mg/dL, % | 20 | 18 | 0.81 |
| Triglyceride/HDL ratio | 4.7 ± 3.9 | 3.0 ± 2.0 | 0.05 |
| >3.0, % | 52.0 | 43.0 | 0.41 |
| No. of metabolic syndrome risk factors, mean ± SD | 2.1 ± 1.2 | 1.8 ± 1.1 | 0.22 |
| 0, % | 12.0 | 10.7 | 0.16 |
| 1, % | 20.0 | 31.9 | |
| 2, % | 20.0 | 31.1 | |
| ≥3, % | 48.0 | 26.3 | |
HOMA, homeostasis model assessment; LDL, low-density lipoprotein; HDL, high-density lipoprotein.