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. 2017 Feb 16;17:140. doi: 10.1186/s12885-017-3121-z

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — S100A4 knockdown abrogates the effects of miR-296 inhibition on EMT, migration and invasion of CRC cells. a miR-296 silenced SW480 cells that were transfected with S100A4 siRNA and scrambled siRNA (scr siRNA) were subjected to western blot. S100A4 siRNA significantly decreased S100A4 in miR-296 silenced SW480 cells, and led to increased E-cadherin expression and decreased Vimentin expression. b S100A4 knockdown significantly inhibited the migration of miR-296 silenced SW480 cells. c S100A4 knockdown significantly inhibited the migration and invasion of miR-296 silenced SW480 cells. n = 3, *P < 0.05