Table 2.
Pre- and post-neoadjuvant CRT physical activity variables
| Physical activity variables | Group | Pre-neoadjuvant CRT | Post-neoadjuvant CRT | Change, % change | p value |
|---|---|---|---|---|---|
| Step count* (steps/day) | Exercise (n = 23) | 5705.3 (3746) | 3723 (2867) | −2755 (4152), −44 (20) | <0.0001 |
| Usual care control (n = 10) | 3701.5 (3569) | 2274 (3690) | −4 (2600), −0.1 (78) | ||
| Overall (n = 33) | 4966 (4435) | 3044.2 (3265) | |||
| MET* | Exercise (n = 23) | 1.4 (0.5) | 1.3 (0.4) | −0.03 (0.3), −2.3 (15) | 0.010 |
| Usual care control (n = 10) | 1.3 (0.9) | 1.1 (0.2) | −0.1 (0.3), −8 (14) | ||
| Overall (n = 33) | 1.3 (0.6) | 1.2 (0.3) | |||
| Active EE (kcal/day)* | Exercise (n = 23) | 229 (482.3) | 152 (153.7) | −115 (499), −30 (93) | 0.003 |
| Usual care control (n = 10) | 354 (443.5) | 244.3 (198.3) | −223 (861), −47 (70) | ||
| Overall (n = 33) | 264.3 (471.3) | 154 (163.9) | |||
| PA duration (min/day) | Exercise (n = 23) | 61 (97.3) | 38 (68) | 31 (105), 8 (140) | 0.45 |
| Usual care control (n = 10) | 69 (83) | 50 (4) | −34 (151), −41 (52) | ||
| Overall (n = 33) | 64 (80.3) | 39 (46) | |||
| Lying down (min/day) | Exercise (n = 23) | 250 (367.3) | 360 (351.7) | 6 (211), 2 (40) | 0.443 |
| Usual care control (n = 10) | 351.4 (432.4) | 541.3 (360.4) | 119 (263), 28 (71) | ||
| Overall (n = 33) | 363 (423.9) | 483.5 (416.5) | |||
| Sleep efficiency (%) | Exercise (n = 7) | 78 (9.1) | 78 (13) | 0.2 (15), 0.3 (21) | 0.917 |
| Usual care control (n = 7) | 69 (20) | 69 (24) | −4 (23), −5 (30) | ||
| Overall (n = 14) | 75 (11) | 73 (22) | |||
| Sleep duration (min/day) | Exercise (n = 23) | 220 (330) | 190 (269) | 0 (141), 0 (35) | 0.847 |
| Usual care control (n = 10) | 264.5 (284) | 265 (315) | 143 (235), 56 (85) | ||
| Overall (n = 33) | 260 (285) | 44 (318) | |||
| Total EE (kcal/day) | Exercise (n = 23) | 1668 (932) | 1701 (921) | −234 (1013), −0.1 (63) | 0.33 |
| Usual care control (n = 10) | 1867 (833) | 1741 (416) | −241 (1019), 7 (147) | ||
| Overall (n = 33) | 1668 (846) | 1707 (722) |
Values are presented as median (IQR). Absolute change (no brackets) and relative (percentage) change (in brackets) are based on the difference between post-neoadjuvant CRT (week 0) and pre-neoadjuvant CRT (baseline) within each group. All data is averaged over the 72-h period of PA monitoring. Note: due to an upgrade in software during data collection, sleep efficiency is reported in 7/23 (exercise) and 7/10 (usual care control)
EE energy expenditure, PA physical activity
*p < 0.05 is taken as statistically significant