Table 3.
Dose (mg/kg) | Liver | Spleen | Kidney | Thymus | |
---|---|---|---|---|---|
Healthy control | - | 6.69 ± 0.16 | 0.60 ± 0.01 | 0.91 ± 0.03 | 0.63 ± 0.04 |
Arthritic control | - | 9.19 ± 0.29β | 1.27 ± 0.04β | 1.35 ± 0.08β | 0.31 ± 0.01β |
Indomethacin | 5 | 7.45 ± 0.40a | 0.81 ± 0.01a | 0.98 ± 0.02a | 0.54 ± 0.01a |
Aqueous extract | 200 | 7.85 ± 0.03 | 0.90 ± 0.05 | 1.12 ± 0.01 | 0.45 ± 0.04 |
400 | 6.61 ± 0.09b | 0.77 ± 0.05a | 0.91 ± 0.09b | 0.54 ± 0.02a | |
Methanol extract | 200 | 7.55 ± 0.30a | 0.89 ± 0.01 | 1.03 ± 0.04a | 0.59 ± 0.06b |
400 | 6.55 ± 0.30c | 0.74 ± 0.14b | 0.93 ± 0.06b | 0.62 ± 0.01b |
Each value represents the mean ± ESM for six animals and analyses by two-way ANOVA followed by Tukey post-hoc test, β P < 0.01 when compared to healthy control, a P < 0.05, b P < 0.01, c P < 0.001 when compared to arthritic control