Table 2.
Relationship between podoplanin expression by tumor cells and clinicopathological parameters.
| Clinicopathological parameters | No. of cases | Podoplanin expression | P-value | |
|---|---|---|---|---|
| Positive | Negative | |||
| Gender | ||||
| Males | 50 | 15 (30%) | 35 (70%) | >0.05 |
| Females | 22 | 7 (32%) | 15 (68%) | |
| Age <60 years | 21 | 10 (48%) | 11 (52%) | >0.05 |
| >60 years | 51 | 13 (25%) | 38 (75%) | |
| Grade | ||||
| Well differentiated (grade I) | 8 | 0 (0%) | 8 (100%) | 0.040 |
| Moderately differentiated (grade II) | 30 | 9 (30%) | 21 (70%) | |
| Poor differentiated (grades III, IV) | 34 | 14 (41%) | 20 (59%) | |
| Stage | ||||
| I | 22 | 7 (32%) | 15 (68%) | >0.05 |
| II | 26 | 11 (42%) | 15 (58%) | |
| III, IV | 26 | 5 (19%) | 21 (81%) | |
| Tumor size | ||||
| <5cm | 46 | 14 (30%) | 32 (70%) | >0.05 |
| >5 cm | 26 | 9 (35%) | 17 (65%) | |
| Vascular invasion | 25 | 6 (24%) | 19 (76%) | >0.05 |
| Cirrhosis | 32 | 13 (41%) | 19 (59%) | >0.05 |
| Chronic hepatitis | 19 | 9 (47%) | 10 (53%) | >0.05 |