Table 4. Single nucleotide polymorphisms and genes whose presence correlates with erythromycin resistance.
| Feature | RF importance | RF p-value | CMH p-value | Annotation | Gene |
|---|---|---|---|---|---|
| og_1652 | 7.180656298 | 0 | 3.701E-14 | ImpB/MucB/SamB family protein | — |
| og_1379 | 7.175992284 | 0 | 6.409E-15 | YolD-like protein | — |
| og_2061 | 7.097377018 | 0 | 6.409E-15 | hypothetical protein | — |
| og_1312 | 6.485953794 | 1.71E-217 | 2.683E-14 | Macrolide efflux pump | mefA |
| og_791 | 6.017699918 | 1.03E-210 | 6.671E-14 | Ribose import ATP-binding protein rbsA | — |
| 1741683 | 4.904707263 | 8.7E-52 | 3.01E-23 | Nudix-related transcriptional regulator NrtR | — |
| og_243 | 4.114250972 | 0.00000718 | 0.0002367 | IS1380-Spn1 transposase | — |
| og_10 | 3.24238261 | 0.000118 | 0.01343 | 3-ketoacyl-ACP reductase | — |
| 290545 | 3.240769624 | 1.2E-76 | 6.7E-12 | Tn916 ORF16 ATP/GTP-binding protein | — |
| 297653 | 3.016787219 | 4.01E-28 | 2.24E-16 | methyltransferase small domain superfamily | — |
| og_53 | 2.971456253 | 5.89E-142 | 4.8E-09 | UDP-glucose 6-dehydrogenase | — |
| og_129 | 2.962230108 | 0.000564 | 4.443E-07 | chlorohydrolase | — |
| 678325 | 2.695815692 | 1.6E-53 | 2.15E-15 | transposase, ISSmi4 | — |
| 136082 | 2.412872116 | 2.23E-15 | 7.73E-14 | cytidine deaminase | cdd |
| 637379 | 2.41015196 | 6.07E-44 | 1.36E-10 | nucleotidyl transferase WchZ | — |
| 987093 | 2.253968194 | 7.1E-12 | 4.43E-23 | Abi-alpha protein | — |
| 2058103 | 1.964208468 | 8.09E-10 | 5.51E-18 | transposase | — |
| og_4190 | 1.95393053 | 0.385 | 0.4235 | IS630-Spn1, transposase Orf1 | — |
| 1593956 | 1.93060019 | 8.68E-09 | 1.62E-10 | Ribose import ATP-binding protein rbsA | — |
| 794795 | 1.754564135 | 0.000000235 | 1.62E-10 | hypothetical protein | — |