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. 2017 Feb 16;7:42213. doi: 10.1038/srep42213

Figure 3. Effects of dmrt1 disruption on gonad phenotype, sex differentiation.

Figure 3

(A) Gross morphology of gonads from approximately one year old fish. (1) dmrt1-deficient ‘testes’; (2) wild-type ovaries; (3) wild-type testes. (B) histology of gonads from approximately one year old fish. (a) dmrt1-deficient testis. The development of testis is ceased. The shape of the dmrt1-deficient testes in transverse sections is similar to control ovaries, and there are structures resembling ovarian cavity and ovarian lamella in the gonad of the mutant male fish. ovarian cavity-like (OCL), ovarian lamella-like (OLL); (b) large magnification of frame area in a. No secondary spermatocytes, spermatids and sperm are observed. oogonia-like (OGL), spermatogonia (SG) and primary spermatocytes (PSC). (c) Ovary of control female, including ovarian cavity (OC), ovarian lamella (OL); (d) large magnification of frame area in (c). Four stages of oocytes: stage I - IV and oogonia (OG). (e) Testis of control male. seminiferous lobuli (SL), seminiferous cyst (SC); (f) larger magnification of frame area in (e). Secondary spermatocytes (SSC), spermatids (ST) and sperm (SM). Scale bar is shown in the figures.