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. 2017 Feb 16;7:42673. doi: 10.1038/srep42673

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Activation of caspases 3, 8 and 9 was detected after 6 h and 24 h of the stimulus of HL-60 (A) and HepG2 (B) cells with CR-LAAO. NC: negative control (non-stimulated cells); PC: positive control (cisplatin at concentrations previously determined by the MTT assay for each cell line: IC₅₀ for HL-60: 2.9 μg/mL; HepG2: 4.0 μg/mL).