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. 2017 Feb 1;10(2):119–126. doi: 10.1242/dmm.027482

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© 2017. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 4. — Impaired novel object recognition and contextual fear memory in Atrx-cHet mice. (A) Percentage alternation and number of arm entries in the Y-maze test by control (n=14) and Atrx-cHet (n=15) female mice. (B) Control (n=14) and Atrx-cHet (n=14) mice displayed similar preference for identical objects in the training session of the novel object recognition task. The Atrx-cHet mice failed to display a preference for the novel object 1.5 and 24 h later (*P<0.05). (C) Atrx-cHet (n=14) mice spent less time immobile than control mice (n=14) in the fear-conditioning paradigm. The total percentage of time spent immobile is shown on the right (*P<0.0001). Statistical analyses made use of Student's two-tailed, unpaired t-test or two-way ANOVA; data are represented as means±s.e.m. and *P<0.05.