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. 2017 Feb 1;10(2):173–183. doi: 10.1242/dmm.027847

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© 2017. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 3. — Pulmonary function tests (PFTs) in ricin-intoxicated pigs. Following intratracheal instillation of ricin (3 µg/kg body weight), respiratory dynamics were measured in non-anesthetized pigs at 0, 18, 24, 30, 42 and 48 hpe by barometric whole-body plethysmography. Control plethysmographic values were determined individually for each of the subjects, prior to intoxication. (A) Respiratory rate (RR). (B) Tidal volume. (C) Minute volume. (D) Peak inspiratory and expiratory flow. (E) Ratio of expiratory time to inspiratory time (E:I). (F) PENH and pause. Values are means±s.e.m., n=5.