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. 2017 Feb 1;10(2):173–183. doi: 10.1242/dmm.027847

Fig. 5.

Fig. 5.

Changes in lung cell composition, proinflammatory cytokines and ET-1 in the BALF of ricin-intoxicated pigs. Bronchioalveolar lavage was performed before or 24 hpe to ricin (3 µg/kg body weight). (A) Cells harvested from the BALF of a representative pig. Note that >99% of the cells at t=0 and at t=24 hpe, are of macrophage and polymorphonuclear origin, respectively. (B) Concentration of the pro-inflammatory cytokines TNF-α, IL-1β and IL-6 in the BALF. (C) Concentration of the peptide vasoconstrictor ET-1 in the BALF. Values are means±s.e.m., n=5. *P<0.05; **P<0.005.