Fig. 4.

CM from Trk- or Tsl-expressing cells induces Tor-dependent activation of STAT92E-driven Fluc activity. CM from cells transfected with vector (Vec) (red), Trk (yellow) or Tsl (green) was applied to S2R+ cells expressing Tor together with the STAT92E-Fluc and R-luc constructs. Some recipient cells were additionally treated with dsRNA targeting Trk (cross-hatched bars), Tsl (hatched bars) or Tor (brickwork bars). Each bar represents an average of three replicates, repeated five times (n=5)±s.d. Comparisons with statistically significant differences are indicated above the bars. *P≤0.05 (P=0.0102), ***P≤0.001. ns, not significant.