Figure 5.

Least squares means plot of individual subjects (a–b) HAM-D scores and scores on the (c–d) Symptom Questionnaire (depression), which significantly predicted levels of gray matter and white matter inorganic phosphate (Pi) in depressed subjects. (a) Gray matter Pi showed no association to HAMD-17 score (t₄₄₆=2.40; p=0.164), and (b) white matter Pi showed a significant negative association (t₁₂₉=−2.63; p=0.095). (c) Analogous to the results from the HAM-D-17, gray matter Pi also showed no association with the SQ (depression) score (t₃₃₉=2.08; p=0.381), whereas (d) white matter Pi showed a highly significant association to the SQ (depression) score (t₁₂₀=−3.98; p=0.001).