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. 2016 Dec 23;6(2):141–147. doi: 10.1242/bio.022186

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© 2017. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 4. — Parp mutation rescues pink1 mutant phenotype. (A) Parp mutation rescues the thoracic defect (asterisks, two-tailed chi-square test, 95% confidence intervals), (B) climbing ability (mean±s.d.; asterisks, two-tailed unpaired t-test) and (C) increases survival of pink1 mutants (n=130 for control, n=114 for pink1, and n=106 for pink1, Parp^CH1/+; asterisks, log-rank Mantel-Cox test). (D) Parp mutation rescues the loss of dopaminergic neurons in the PPL1 cluster of pink1 mutant flies (mean±s.e.m.; asterisks, one-way ANOVA with Bonferroni's multiple comparison test). (E) Representative images of anti-tyrosine hydroxylase-stained PPL1 cluster neurons are shown for the indicated genotypes. Genotypes: control: w¹¹¹⁸, pink1: pink1^B9, pink1, parp^CH1/+: pink1^B9, Parp^CH1/+. Dataset in D labelled ‘control’ has been previously published in Lehmann et al. (2016), as data were obtained as a single experimental set before statistical analysis.