Table 2.
Immunohistochemical characteristics of the derma of progressive psoriatic lesions, remission of psoriasis and healthy individuals
| Group | Patients with pro gressive
psoriatic lesions (Pr) |
Psoriasis patients in remission (R) |
Healthy individuals (H) |
p-value** | ||
|---|---|---|---|---|---|---|
| Pr vs R | Pr vs H | R vs H | ||||
| Number of positive cells, Х (x0.25-x0.75)*: Ki67+ |
40 (22-54) | 7 (4-13) | 3 (2-6) | 9.7 x 10-13 | 1.33 x 10-14 | 8.9 x 10-11 |
| CD3ε+Ki67+ T-cells |
12 (5-17) | 2 (1-3) | 0 | 3.3 x 10-15 | 1.3 x 10-14 | 2.2 x 10-5 |
| CD45RA+ (naïve T-cells) |
25 (15-30) | 8 (3-11) | 3 (1-4) | 1.7 х 10-13 | 4.4 х 10-13 | 2.5 х 10-6 |
| CD45RO+ (effector/memory T-cells) |
208 (152-268) | 59 (41-73) | 15 (11-21) | 3.5 х 10-11 | 6.7 х 10-14 | 2.8 х 10-8 |
| Number of examined samples |
41 | 18 | 16 | |||