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. 2017 Jan 25;81(1):e00048-16. doi: 10.1128/MMBR.00048-16

FIG 23.

FIG 23

Differential control of Irr-repressed genes by the variable affinity of Irr for target promoters. Low-affinity promoters such as those found in the housekeeping gene leuC or pbgS allow some expression (derepression) even under low-iron conditions, where Irr levels are highest. High-affinity promoters such as those found for mbfA and bfr repress expression strongly at low and intermediate levels of iron and are derepressed only at high iron levels.