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. 2017 Jan 19;8(2):346–359. doi: 10.1016/j.stemcr.2016.12.015

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© 2017 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Transdifferentiation Core Gene Signatures of B Cells Induced with C/EBP Family Members

Quantification of mRNA from GFP⁺-sorted B cells 24 hr after transduction with individual C/EBPs. Venn diagram of (A) upregulated and (B) downregulated genes, compared with empty vector (MIG) control. Overlapping core signatures of (C) 22 upregulated or (D) 12 downregulated genes. Key myeloid (in C) and lymphoid (in D) genes are shown in bold. The fold change (FC) relative to empty vector (MIG)-transduced B cells is shown. See also Table S1.

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