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. 2016 Jul 6;7(37):58931–58938. doi: 10.18632/oncotarget.10431

Figure 2. lncRNA-CLMAT3 knockdown inhibited CRC growth in vitro.

Figure 2

(A) lncRNA-CLMAT3 knockdown suppressed CRC growth in vitro. CCK8 assays were performed to determine the proliferation of CRC cells transfected with lncRNA-CLMAT3 shRNA and control shRNA. **P < 0.01 compared with control shRNA. (B) Colony-forming growth assays were also performed to assess CRC cell proliferation. The colonies were imaged and counted. **P < 0.01 compared with control shRNA. (C) Proliferating LOVO cells were labeled with EdU. The click-it reaction revealed EdU staining (red). The cell nuclei were stained with DAPI. The images are representative of the results obtained. **P < 0.01 compared with control shRNA.