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. 2016 Jul 28;7(37):59070–59086. doi: 10.18632/oncotarget.10887

Figure 2. Selection strategy for target genes of miR-101.

Figure 2

Analysis using the TargetScan program showed that 3,013 genes had putative target sites for miR-101 in their 3′ UTRs. Among these genes, 790 had conserved target sites among vertebrates for miR-101. Then, we assessed the expression levels of these genes in RCC clinical specimens using GEO expression profiles (GSE36985 and GSE22541). Finally, genes upregulated in RCC (log2 ratio > 1.0) were selected as putative target genes.