Table 1. Characteristics of the sample population.
Entire cohort (n = 43,802) | Patients using statins (≥ 28 cDDDs; n = 10,086) | Patients not using statins (< 28 cDDDs; n = 33,716) | Pa | ||||
---|---|---|---|---|---|---|---|
n | % | n | % | n | % | ||
Age, years (mean ± SD) | 62.92 (13.18) | 61.55 (10.97) | 63.33 (13.74) | < 0.001 | |||
40–54 | 14458 | 33.01 | 3180 | 31.53 | 11278 | 33.45 | < 0.001 |
55–64 | 9644 | 22.02 | 2899 | 28.74 | 6745 | 20.01 | |
65–74 | 10455 | 23.87 | 2777 | 27.53 | 7678 | 22.77 | |
≥ 75 | 9245 | 21.11 | 1230 | 12.20 | 8015 | 23.77 | |
Sex | |||||||
Female | 19715 | 45.01 | 5150 | 51.06 | 14565 | 43.20 | < 0.001 |
Male | 24087 | 54.99 | 4936 | 48.94 | 19151 | 56.80 | |
CCI+ | |||||||
0 | 11279 | 25.75 | 2586 | 25.64 | 8693 | 25.78 | < 0.001 |
1 | 12597 | 28.76 | 3014 | 29.88 | 9583 | 28.42 | |
2 | 9075 | 20.72 | 2195 | 21.76 | 6880 | 20.41 | |
≥ 3 | 10851 | 24.77 | 2291 | 22.71 | 8560 | 25.39 | |
Diabetes | |||||||
No | 33491 | 76.46 | 6819 | 67.61 | 26672 | 79.11 | < 0.001 |
Yes | 10311 | 23.54 | 3267 | 32.39 | 7044 | 20.89 | |
Hypertension | |||||||
No | 22067 | 50.38 | 4158 | 41.23 | 17909 | 53.12 | < 0.001 |
Yes | 21735 | 49.62 | 5928 | 58.77 | 15807 | 46.88 | |
Dyslipidemia | |||||||
No | 31731 | 72.44 | 5785 | 57.36 | 25946 | 76.95 | < 0.001 |
Yes | 12071 | 27.56 | 4301 | 42.64 | 7770 | 23.05 | |
Nonstatin lipid-lowering drugs | |||||||
< 28 days | 39267 | 89.65 | 7212 | 71.51 | 32055 | 95.07 | < 0.001 |
28–365 days | 3186 | 7.27 | 1923 | 19.07 | 1263 | 3.75 | |
> 365 days | 1349 | 3.08 | 951 | 9.43 | 398 | 1.18 | |
Metformin | |||||||
< 28 days | 35961 | 82.10 | 6286 | 62.32 | 29675 | 88.01 | < 0.001 |
28–365 days | 2684 | 6.13 | 964 | 9.56 | 1720 | 5.10 | |
> 365 days | 5157 | 11.77 | 2836 | 28.12 | 2321 | 6.88 | |
ACEI | |||||||
< 28 days | 23928 | 54.63 | 3066 | 30.40 | 20862 | 61.88 | < 0.001 |
28–365 days | 7925 | 18.09 | 1928 | 19.12 | 5997 | 17.79 | |
> 365 days | 11949 | 27.28 | 5092 | 50.49 | 6857 | 20.34 | |
Aspirin | |||||||
< 28 days | 28319 | 64.65 | 4161 | 41.26 | 24158 | 71.65 | < 0.001 |
28–365 days | 7385 | 16.86 | 2296 | 22.76 | 5089 | 15.09 | |
> 365 days | 8098 | 18.49 | 3629 | 35.98 | 4469 | 13.25 | |
Urbanization level | |||||||
Urban | 30539 | 69.72 | 7208 | 71.47 | 23331 | 69.20 | < 0.001 |
Suburban | 8914 | 20.35 | 1920 | 19.04 | 6994 | 20.74 | |
Rural | 4349 | 9.93 | 958 | 9.50 | 3391 | 10.06 | |
Monthly income (NT$) | |||||||
0 | 3464 | 7.91 | 795 | 7.88 | 2669 | 7.92 | < 0.001 |
1–21,000 | 15001 | 34.25 | 3067 | 30.41 | 11934 | 35.40 | |
21,000–33,300 | 12904 | 29.46 | 3165 | 31.38 | 9739 | 28.89 | |
≥ 33,301 | 12433 | 28.38 | 3059 | 30.33 | 9374 | 27.80 |
Comparison between statin use and no statin use.
CCI: Charlson comorbidity index.