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. 2016 Aug 9;7(37):59618–59629. doi: 10.18632/oncotarget.11162

Table 1. Characteristics of the sample population.

Entire cohort (n = 43,802) Patients using statins (≥ 28 cDDDs; n = 10,086) Patients not using statins (< 28 cDDDs; n = 33,716) Pa
n % n % n %
Age, years (mean ± SD) 62.92 (13.18) 61.55 (10.97) 63.33 (13.74) < 0.001
 40–54 14458 33.01 3180 31.53 11278 33.45 < 0.001
 55–64 9644 22.02 2899 28.74 6745 20.01
 65–74 10455 23.87 2777 27.53 7678 22.77
 ≥ 75 9245 21.11 1230 12.20 8015 23.77
Sex
 Female 19715 45.01 5150 51.06 14565 43.20 < 0.001
 Male 24087 54.99 4936 48.94 19151 56.80
CCI+
 0 11279 25.75 2586 25.64 8693 25.78 < 0.001
 1 12597 28.76 3014 29.88 9583 28.42
 2 9075 20.72 2195 21.76 6880 20.41
 ≥ 3 10851 24.77 2291 22.71 8560 25.39
Diabetes
 No 33491 76.46 6819 67.61 26672 79.11 < 0.001
 Yes 10311 23.54 3267 32.39 7044 20.89
Hypertension
 No 22067 50.38 4158 41.23 17909 53.12 < 0.001
 Yes 21735 49.62 5928 58.77 15807 46.88
Dyslipidemia
 No 31731 72.44 5785 57.36 25946 76.95 < 0.001
 Yes 12071 27.56 4301 42.64 7770 23.05
Nonstatin lipid-lowering drugs
 < 28 days 39267 89.65 7212 71.51 32055 95.07 < 0.001
 28–365 days 3186 7.27 1923 19.07 1263 3.75
 > 365 days 1349 3.08 951 9.43 398 1.18
Metformin
 < 28 days 35961 82.10 6286 62.32 29675 88.01 < 0.001
 28–365 days 2684 6.13 964 9.56 1720 5.10
 > 365 days 5157 11.77 2836 28.12 2321 6.88
ACEI
 < 28 days 23928 54.63 3066 30.40 20862 61.88 < 0.001
 28–365 days 7925 18.09 1928 19.12 5997 17.79
 > 365 days 11949 27.28 5092 50.49 6857 20.34
Aspirin
 < 28 days 28319 64.65 4161 41.26 24158 71.65 < 0.001
 28–365 days 7385 16.86 2296 22.76 5089 15.09
 > 365 days 8098 18.49 3629 35.98 4469 13.25
Urbanization level
 Urban 30539 69.72 7208 71.47 23331 69.20 < 0.001
 Suburban 8914 20.35 1920 19.04 6994 20.74
 Rural 4349 9.93 958 9.50 3391 10.06
Monthly income (NT$)
 0 3464 7.91 795 7.88 2669 7.92 < 0.001
 1–21,000 15001 34.25 3067 30.41 11934 35.40
 21,000–33,300 12904 29.46 3165 31.38 9739 28.89
 ≥ 33,301 12433 28.38 3059 30.33 9374 27.80
a

Comparison between statin use and no statin use.

+

CCI: Charlson comorbidity index.