Table 3. Univariate and multivariate analysis of overall survival of patients.

Characteristic	Univariate analysis		Multivariate analysis
	HR (95% CI)	P value	HR (95% CI)	P value
Sex (male vs. female)	1.190 (0.536–2.641)	0.669	0.658 (0.256–1.693)	0.385
Age (< 60 vs. ≥ 60 years)	1.071 (0.536–2.140)	0.846	1.004 (0.462–2.181)	0.993
Smoking status	1.984 (0.963–4.086)	0.063	2.627 (1.147–6.013)	0.022
SCC	0.757 (0.369–1.556)	0.449	0.698 (0.328–1.485)	0.351
Cyfra-21-1	0.847 (0.591–1.290)	0.497	0.773 (0.421–1.419)	0.406
miR-324-3p	2.169 (1.072–4.388)	0.031	3.039 (1.340–6.894)	0.008
miR-1285	0.606 (0.304–1.209)	0.155	0.572 (0.277–1.180)	0.130