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. 2016 Aug 5;7(37):60110–60122. doi: 10.18632/oncotarget.11076

Figure 2. sst5TMD4 overexpression increases the expression of pro-angiogenic factors and the number of blood vessels in xenografted breast cancer cell line-derived tumors.

Figure 2

A. sst5TMD4 protein expression by western blotting in mock- and sst5TMD4-MCF-7 xenografted tumors. B. Expression levels of EGF and VEGF in xenografts derived from mock- and sst5TMD4-MCF-7 cells measured by qPCR. C. and D. VEGF protein expression by western blotting and IHF in mock- and sst5TMD4-MCF-7 xenografted tumors. E. Representative images (x20) and quantification of straight blood vessels in xenografts derived from mock- and sst5TMD4-MCF-7 cells. Data represent mean ± SEM of n=4-5 samples. Asterisks (*, p<0.05) indicate significant differences between sst5TMD4- and mock-transfected tumors.