Skip to main content
. 2016 Aug 5;7(37):60110–60122. doi: 10.18632/oncotarget.11076

Figure 4. sst5TMD4 protein levels are associated to higher expression of pro-angiogenic factors and the presence of lymphatic metastasis in breast cancer samples.

Figure 4

A. A TMA including the 117 breast carcinoma samples was employed to determine the presence of sst5TMD4 at the protein level by using an sst5TMD4 specific custom-made antibody and of the angiogenic marker CD34. Representative pictures (x20) of sst5TMD4 and CD34 staining in low and high sst5TMD4 expressors are depicted. B. Association between presence and expression of sst5TMD4 at protein and mRNA levels in the battery of breast carcinoma samples. C. Association between the presence of sst5TMD4 and CD34 and lymphatic metastasis in breast carcinoma samples. Graphs, obtained from a frequency table, show the distribution of 117 grade 3 breast carcinoma with low or high sst5TMD4 protein levels according to CD34 staining and lymphatic metastasis. D. Kaplan-Meier plots showing the association of increased sst5TMD4 by IHC and disease-free survival (DFS) in breast carcinoma series. Significant correlation was studied using a Chi-square and Long-rank-p-value methods.